Table 2

Classification of outcome in PROGRAMS at 2 years of age corrected for prematurity

GM-CSF – control
OutcomeGM-CSF (n=139)Control (n=141)RR95% CI
Death33/13424%31/14122%1.10.7 to 1.7
Survival without severe disability87/13465%87/13166%1.00.8 to 1.2
Survival without disability63/13447%68/13152%0.90.7 to 1.2
Overall function in survivors
 Severe disability14/10114%13/10013%1.2§0.5 to 2.7
 Other disability24/10124%19/10019%1.4§0.7 to 2.7
 No disability63/10162%68/10068%
Neurological abnormality7/1017%9/1009%0.80.3 to 2.0
  • * Unable to trace or abroad.

  • One not done, two assessed by non-study paediatrician but insufficient information to classify disability.

  • Using criteria outlined in references 11 and 12. Malformation and growth domains have been excluded from the disability criteria.

  • § RR ratio estimated by multinomial logistic regression.

  • GM-CSF, granulocyte-macrophage colony-stimulating factor.