Table 1

Multinomial logistic regression (parity=primigravid included in model)

	Controls		Grade 1 NE				Grade 2 NE				Grade 3 NE				Grades 2 and 3 NE
Variable	N	RRR	N	RRR	95% CI	p Value	N	RRR	95% CI	p Value	N	RRR	95% CI	p Value	N	RRR	95% CI	p Value
PW/BW (continuous variable)	307	Ref	75	1.21	1.06 to 1.37	<0.01	45	1.20	1.04 to 1.68	<0.05	18	1.05	0.85 to 1.28	NS	63	1.23	1.07 to 1.42	<0.01
Gestation (continuous variable)	309	Ref	76	0.80	0.65 to 0.98	<0.05	46	0.95	0.72 to 1.25	NS	19	0.58	0.42 to 0.81	<0.01	65	0.78	0.62 to 1.00	0.056
Male gender	155	Ref	41	1.38	0.72 to 2.68	NS	31	3.39	1.43 to 8.04	<0.01	11	1.3	0.41 to 4.16	NS	42	2.29	1.01 to 5.26	0.046
Maternal age ≥30 years	94	Ref	31	0.87	0.43 to 1.76	NS	23	1.09	0.47 to 2.53	NS	10	1.56	0.50 to 4.87	NS	33	1.21	0.54 to 2.72	NS
Mode of delivery (emergency section or instrumental)	161	Ref	61	6.39	2.78 to 14.64	<0.001	34	3.74	1.46 to 9.59	<0.01	14	3.55	1.01 to 12.45	0.048	48	3.56	1.41 to 9.42	<0.01
Maternal diabetes	2	Ref	2	0.55	0.03 to 10.64	NS	0	^*	^*	^*	2	4.55	0.21 to 98.33	NS	2	^*	^*	^*
Maternal hypertension	2	Ref	1	1.85	0.12 to 29.78	NS	2	11	1.08 to 111.31	<0.05	1	22.68	1.29 to 396.24	<0.05	3	9.65	0.95 to 98.44	0.043
Maternal pre-eclampsia	6	Ref	5	5.50	1.11 to 27.09	<0.05	0	^*	^*	^*	0	^*	^*	^*	0	^*	^*	^*
Haemorrhage (all locations)	24	Ref	15	3.83	1.48 to 9.92	<0.01	9	3.5	1.10 to 11.04	<0.05	8	6.71	1.85 to 24.46	<0.01	17	3.55	1.10 to 11.45	<0.05
Infarction	77	Ref	19	0.61	0.28 to 1.32	NS	11	0.53	0.21 to 1.37	NS	9	2.36	0.73 to 7.65	NS	20	1.02	0.43 to 2.42	NS
Infection/inflammation (any indicator)	116	Ref	46	2.16	1.11 to 4.19	<0.05	25	1.25	0.56 to 2.80	NS	7	0.96	0.29 to 3.11	NS	32	1.06	0.48 to 2.33	NS
Meconium phagocytosis	16	Ref	21	7.18	2.90 to 17.74	<0.001	18	11.44	4.26 to 30.66	<0.001	4	9.82	2.27 to 42.35	<0.01	22	13.18	4.89 to 35.46	<0.001

Variables for meconium staining and birth weight excluded from multivariate analysis due to multicollinearity.
RRR, (in comparison with controls) adjusted for other variables listed.
↵* RRR could not be computed.
NE, neonatal encephalopathy; NS, not significant; Ref, reference.