Culture-positive rates for the combinations of the line segments and their positive and negative predictive values for catheter-related sepsis and colonisation
| Combination of PCVL segments | Overall group (n=189) | PPV for CRS and colonisation in overall group (n =189)% (95% CI) | NPV for CRS and colonisation in overall group (n =189)% (95% CI) | Suspected sepsis group (n=47) | PPV for definite CRS in suspected sepsis group (n =47)% (95% CI) | NPV for definite CRS in suspected sepsis group (n =47)% (95% CI) |
|---|---|---|---|---|---|---|
| Proximal+Tip | 56 (30)* | 27 (16 to 40) | 100 (97 to 100) | 23 (49) | 65 (43 to 84) | 100 (86 to 100)† |
| Middle+Tip | 51 (30) | 29 (18 to 44) | 100 (97 to 100) | 24 (51) | 63 (41 to 81) | 100 (85 to 100)† |
| Proximal+Middle | 49 (26) | 22 (12 to 37)*** | 97 (92 to 99) | 16 (34) | 69 (41 to 89) | 87 (70 to 96) |
| Proximal+Middle+Tip | 61 (32)** | 25 (14 to 37) | 100 (97 to 100) | 24 (51) | 63 (41 to 81) | 100 (85 to 100)† |
| Tip | 36 (19) | 36 (21 to 54) | 99 (95 to 99) | 20 (43) | 65 (41 to 85) | 93 (76 to 99) |
Culture data are n (%) culture-positive segments where ≥1 line segment is positive within any combination.
Versus tip alone:
↵* p=0.01;
↵** p=0.003;
↵*** p=0.03;
↵† p=0.007.
CRS, catheter-related sepsis; NPV, negative predictive value; PCVL, percutaneous central venous line; PPV, positive predictive value.