Table 4

Characteristics of seizure burden in non-cooled and cooled groups

All neonatesNon-cooled (n=16)Cooled (n=15)p Value
Recorded seizure burden (min)203 (141–406)60 (39–224)0.027
Total seizure numbers per neonate75 (42–180)41 (12–161)0.105
Mean seizure duration (s) per neonate200 (101–324)142 (85–274)0.192
Number of neonates with status epilepticus940.095*
Age onset of EEG (h)15 (5-20)6 (3-9)0.006
Total EEG duration (h)55 (41–60)88 (75–101)0.001
Moderate HIENon-cooled (n=6)Cooled (n=8)p Value
Recorded seizure burden (min)162 (97–262)49 (26–89)0.020
Total seizure numbers per neonate42 (17–74)15(3-40)0.174
Mean seizure duration (s) per neonate362 (168–513)258 (87–759)0.519
Severe HIENon-cooled (n=10)Cooled (n=7)p Value
Recorded seizure burden (min)223 (172–720)224 (60–289)0.558
Total seizure numbers per neonate136 (56–203)161 (41–185)0.591
Mean seizure duration (s) per neonate137 (98–293)108 (79–168)0.172
  • Data are median (IQR) or n.

  • * χ2 test for the proportion of neonates with status epilepticus in non-cooled and cooled groups.