Numbers of culture-positive line segments and their positive and negative predictive values for the various groups
| PCVL segment | All lines n=189 | Well baby, colonised line n=37 | Unwell baby, clinical sepsis n=47 | PPV for CRS and colonisation% (95% CI) | NPV for CRS and colonisation% (95% CI) | PPV for definite CRS% (95% CI) | NPV for definite CRS% (95% CI) |
|---|---|---|---|---|---|---|---|
| Tip | 36 (19) | 16 (43) | 20 (43)** | 36 (21 to 54)* | 99 (95 to 100) | 65 (41 to 85) | 93 (76 to 99)† |
| Mid | 34 (18) | 20 (54) | 14 (30) | 27 (13 to 44) | 96 (92 to 97) | 64 (35 to 87) | 82 (64 to 93)‡ |
| Proximal | 40 (21) | 29 (78)* | 11 (23) | 20 (9 to 36) | 95 (91 to 98) | 73 (39 to 94) | 81 (64 to 92) |
Culture data are n (%) of culture-positive segments of each type.
Tips versus proximal segments:
↵* p=0.004,
↵** p=0.14, for n=47 with suspected sepsis and n=15 with definite CRS,
↵*** p=0.04,
↵† p=0.01.
Tip versus mid-segment:
↵‡ p=0.02.
CRS, catheter-related sepsis; NPV, negative predictive value; PCVL, percutaneous central venous line; PPV, positive predictive value.