Outcome indictors by CPAP weaning method (intension to treat multivariate analysis n=177)
| M1 (n=56) | m2 (n=69) | M3 (n=52) | Sig | |
|---|---|---|---|---|
| Time of wean‡ | 11.3±0.8 | 16.8±1.0* | 19.4±1.3* | p<0.0001 |
| Total days CPAP | 24.4±0.1 | 38.6±0.1* | 30.5±0.1* | p<0.0001 |
| CGA OFF CPAP | 31.9±0.1 | 34.1±0.1* | 32.8±0.2* | p<0.0001 |
| Oxygen duration‡ | 24.1±1.5 | 45.8±2.2* | 34.1±2.0* | p<0.0001 |
| BPD | 7/56 (12.5%) | 29/69 (42%)† | 10/52 (19%) | p=0.011 |
| Length of Admission$ | 58.5±0.1 | 73.8±0.1* | 69.5±0.1* | p<0.0001 |
| CGA at D/C# | 35.8±0.1 | 36.9±0.1* | 36.9±0.1* | p<0.0001 |
Adjusted for gender and Apgar scores at 1 and 5 min within a generalised linear model.
↵* Significantly longer/more than M1 p<0.001, †p<0.01 (Bonferroni adjusted).
Estimated marginal means±1SE, ‡days, $days in level 3 intensive care and #D/C, discharge.
CGA, corrected GA; CPAP, continuous positive airway pressure.