Table 4

OR associated with NEC for neurological or bowel problems reported by parents in the ORACLE Children Study

NECNo NECUnadjusted modelModel 1 (antenatal factors)Model 2 (antenatal and neonatal factors)
n=118n=6316OR(95% CI)OR(95% CI)OR(95% CI)
Cerebral palsy8 (6.8%)159 (2.5%)2.77(1.33, 5.77)1.23(0.58 to 2.63)0.87(0.39 to 1.95)
Seizures13 (11.0%)460 (7.3%)1.55(0.86, 2.77)1.68(0.93 to 3.02)1.24(0.67 to 2.29)
ADHD18 (15.3%)462 (7.3%)2.24(1.34, 3.72)2.08(1.22 to 3.54)1.60(0.92 to 2.78)
Any bowel problem18 (15.3%)202 (3.2%)5.34(3.17, 8.98)3.69(2.12 to 6.43)3.61(2.08 to 6.25)
Bowel stoma6 (5.1%)79 (1.3%)4.16(1.78, 9.73)2.46(1.01 to 6.03)2.35(0.96 to 5.74)
Other bowel problems12 (10.2%)123 (1.9%)5.59(3.00, 10.4)4.30(2.21 to 8.37)3.96(2.06 to 7.61)
  • No missing data.

  • ADHD, attention deficit hyperactivity disorder; NEC, necrotising enterocolitis.