Neurodevelopmental outcome of total cohort, cohorts I and II, and AGA and SGA infants
| By cohort | By gestational age | ||||||
|---|---|---|---|---|---|---|---|
| Total cohort, n=101 | Cohort I, n=45 | Cohort II, n=56 | Cohort I vs II, p value | AGA, n=45 | SGA, n=56 | AGA vs SGA, p value | |
| Outcome CA | |||||||
| Normal, n (%) | 75 (74.3) | 38 (84.4) | 37 (66.1) | 0.051 | 39 (86.7) | 36 (64.3) | 0.020* |
| Mildly delayed, n (%) | 21 (20.8) | 7 (15.6) | 14 (25.0) | 4 (8.9) | 17 (30.4) | ||
| Severely delayed, n (%) | 5 (5.0) | 0 | 5 (8.9) | 2 (4.4) | 3 (5.4) | ||
| Outcome UCA | |||||||
| Normal, n (%) | 43 (42.6) | 18 (40.0) | 25 (44.6) | 0.079 | 21 (46.7) | 22 (39.3) | 0.359 |
| Mildly delayed, n (%) | 41 (40.6) | 23 (51.1) | 18 (32.1) | 19 (42.2) | 22 (39.2) | ||
| Severely delayed, n (%) | 17 (16.8) | 4 (8.9) | 13 (23.2) | 5 (11.1) | 12 (21.4) | ||
Total cohort: infants born in 1996–2005; cohort I: 1996–2000; cohort II: 2001–2005.
Outcome: Griffiths Mental Development Scales, Developmental Quotient, locomotor subscale excluded and Bayley Scales of Infant Development-Second Edition, Mental Developmental Index.
Normal: ≤−1 Z score ≥0, performance within −1 SD or >0 SD; mildly delayed: >−1 Z score ≤−2, performance within −1 and −2 SD; severely delayed: Z score >−2, performance more than −2 SD.
↵* p<0.05.
AGA, appropriate for gestational age, ≥p10; CA, corrected age for prematurity; SGA, small for gestational age, <p10; UCA, uncorrected age.