Table 1

Characteristics of 101 surviving children assessed at 2 years corrected age: total cohort, cohort I and II, and AGA and SGA infants

By cohortBy gestational age
Total cohort (n=101), n (%)Cohort I (n=45), n (%)Cohort II (n=56), n (%)Cohort I vs II, p valueAGA (n=45), n (%)SGA (n=56), n (%)AGA vs SGA, p value
Median maternal age (years) (min–max)30.0 (17–45)29.0 (19–43)31.0 (17–45)0.19829.0 (19–43)31.0 (17–45)0.173
Median birth weight (g) (min–max)675 (480–750)649 (480–750)685 (540–750)0.025720 (580–750)635 (480–750)<0.001
Median gestational age (weeks) (min-max)28.00 (24.84–34.42)27.84 (24.84–34.42)28.21 (25.0–34.14)0.20526.70 (24.84–29.42)28.84 (26.28–34.42)<0.001
Multiple birth20 (19.8)8 (17.8)12 (21.4)0.80313 (28.9)7 (12.5)0.048
Male45 (44.6)20 (44.4)25 (44.6)1.00015 (33.3)30 (53.6)0.047
Ethnicity (Caucasian)93 (92.1)43 (95.6)50 (89.3)0.29340 (88.9)53 (94.6)0.461
Socio-economic status0.5150.429
 High21 (21.0)7 (15.6)14 (25.5)9 (20.5)6 (10.7)
 Average64 (64.0)31 (68.9)33 (60.0)26 (59.1)38 (67.9)
 Low15 (15.0)7 (15.6)8 (14.5)9 (20.5)12 (21.4)
Maternal educational level0.0190.308
 High12 (17.9)1 (3.3)11 (29.7)5 (15.6)7 (20.0)
 Average28 (41.8)14 (46.7)14 (37.8)11 (34.4)17 (48.6)
 Low27 (40.3)15 (50.0)12 (32.4)16 (50.0)11 (31.4)
Prenatal steroids (GA <32 weeks)81 (86.2)34 (82.9)47 (88.7)0.54939 (86.7)42 (85.7)1.000
Caesarean delivery83 (82.2)36 (80.0)47 (83.9)0.79427 (60.0)56 (100)<0.001
5 Min Apgar score <712 (11.9)6 (13.3)6 (10.7)0.7628 (17.8)4 (7.1)0.127
SGA56 (55.4)22 (48.9)34 (60.7)0.314
  • Total cohort: infants born in 1996–2005; cohort I: 1996–2000; cohort II: 2001–2005. Maternal educational level was available in 87.1% of infants.

  • AGA, appropriate for gestational age, ≥p10; GA, gestational age; SGA, small for gestational age, <p10.