Lower and upper limits of target VT for four different clinical scenarios
| Lower limit target VT (ml/kg) | Upper limit target VT (ml/kg) | |||||
|---|---|---|---|---|---|---|
| Median | IQR | Range | Median | IQR | Range | |
| Birth weight 600 g and RDS (n=22) | 4.0 | 3.4–4.0 | 2.0–5.0 | 5.0 | 4.9–6.0 | 4.0–8.0 |
| Birth weight 1200 g and RDS (n=22) | 4.0 | 3.5–4.0 | 2.0–5.0 | 5.25 | 4.5–6.0 | 4.0–6.0 |
| Weaning (n=24) | 3.75 | 3.5–4.0 | 3.0–5.0 | 5.0 | 4.5–6.0 | 4.0–8.0 |
| Ventilator-dependent BPD (n=20) | 4.0 | 3.5–4.4 | 2.0–6.0 | 6.0* | 5.0–8.0 | 4.0–10.0 |
↵* Upper limit target VT for BPD was higher in comparison to upper limit for RDS and weaning, p=0.045 by Mann–Whitney test.
BPD, bronchopulmonary dysplasia; RDS, respiratory distress syndrome; VT, tidal volume.