Potential risk factors for LOGNS on univariate analysis
| Cases (N=48) | Control (N=96) | p Value | |
|---|---|---|---|
| Mechanical ventilation | 92% (44) | 77% (74) | 0.05 |
| Days of ventilation (mean, 95% CI) | 13.9 (9.4 to 18.5) | 6.6 (5.0 to 8.25) | 0.001 |
| nCPAP | 35% (17) | 54% (54) | 0.2 |
| Days of nCPAP (mean, 95% CI) | 14 (6 to 23) | 8 (5 to 11) | 0.1 |
| Age started enteral feeds (day of life; mean, 95% CI) | 7 (5 to 9) | 5 (4 to 6) | 0.04 |
| TPN | 90% (43) | 74% (71) | 0.02 |
| Days of TPN (mean, 95% CI) | 16.5 (9.7 to 23.2) | 6.3 (5.1 to 7.6) | <0.001 |
| Central line | 96% (46) | 80% (77) | 0.02 |
| Days central line (mean, 95% CI) | 16.7 (9.9 to 23.4) | 7.6 (6.3 to 8.9) | <0.001 |
| NEC | 27% (13) | 7.3% (7) | 0.001 |
| Any antibiotic use | 96% (46) | 96% (92) | 0.7 |
| Vancomycin use | 42% (20) | 22% (21) | 0.02 |
| Tazocin use | 29% (14) | 12.5% (12) | 0.02 |
Unless otherwise indicated, data are presented as % (number).
LOGNS, late onset gram-negative sepsis and meningitis; nCPAP, nasal continuous positive airway pressure; NEC, necrotising enterocolitis; TPN, total parenteral nutrition.