Linear regression coefficients from a multivariate regression analysis showing the association between weight loss at day 3 as dependent variable, and maternal, obstetric and neonate's characteristics with a stratification by feeding mode
| Tests for interactions | Model 1: all neonates, n=1495 | Model 2: breastfed neonates (exclusively breastfed or mixed- feeding (breast and formula)), n=1084 | Model 3: formula-fed neonates (exclusively formula), n=411 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Parameter | Interaction p value* | Linear regression coefficient | SE | p Value | Linear regression coefficient | SE | p Value | Linear regression coefficient | SE | p Value | |
| Maternal characteristics | |||||||||||
| Recruitment centre | Poitiers vs nancy | <0.0001 | –† | – | – | 1.07 | 0.17 | <0.0001 | −0.43 | 0.25 | 0.09 |
| Age at delivery | For 10 years | 0.19 | 0.46 | 0.16 | 0.004 | – | – | – | – | – | – |
| Parity | Multipara vs primipara | 0.0008 | – | – | – | −0.81 | 0.18 | <0.0001 | 0.35 | 0.27 | 0.20 |
| Pre-pregnancy BMI | For 10 kg/m2 | 0.0002 | – | – | – | 0.68 | 0.20 | 0.0007 | −0.65 | 0.28 | 0.02 |
| Gestational diabetes | Yes vs no | 0.83 | 0.64 | 0.29 | 0.03 | ||||||
| Gestational weight gain | For 10 kg | 0.12 | – | – | – | 0.45 | 0.18 | 0.01 | −0.05 | 0.25 | 0.84 |
| Obstetric characteristics | |||||||||||
| Method of delivery | Planned caesarean section vs vaginal | 0.29 | 1.53 | 0.29 | <0.0001 | – | – | – | – | – | – |
| Emergency caesarean section vs vaginal | 0.72 | 0.25 | 0.004 | – | – | – | – | – | – | ||
| Infant characteristics | |||||||||||
| Sex | Male vs female | 0.13 | – | – | – | −0.10 | 0.17 | 0.54 | −0.57 | 0.24 | 0.02 |
| Gestational age | For 1 week of gestation | 0.25 | −0.40‡ | 0.06 | <0.0001 | – | – | – | – | – | – |
| Birth weight | For 1 kg | 0.56 | 1.07‡ | 0.18 | <0.0001 | – | – | – | – | – | – |
↵* Interaction p value between each explanatory variable and feeding mode, tested in all the neonates.
↵† Due to the significant interactions, it is inappropriate to provide these estimates.
↵‡ The interpretation is, for example in model 1: D3WL decreases 0.4 % for each additional week of gestation (β=−0.4): while D3WL increases of 1.07 % for a 1 kg difference (β=1.07).