Table 2 Univariate and multivariate odds ratio for mortality and composite outcome
VariableAssociation with mortalityAssociation with mortality or severe IVH, cystic PVL, surgical NEC or GI perforation
Univariate OR (95% CI)Adjusted OR (95% CI)Univariate ORAdjusted OR (95% CI)
Hypotension treatment9.9 (3.4 to 28), p<0.0019.7 (2.6 to 36), p<0.00112.9 (3.9 to 43), p<0.0019.7 (2.6 to 36), p<0.001
Gestational age*0.67 (0.50 to 0.89), p = 0.0060.94 (0.58 to 1.5)0.71 (0.55 to 0.92), p = 0.0080.94 (0.58 to 1.5)
SGA†1.3 (0.44 to 3.9)0.86 (0.2 to 3.6)1.7 (0.59 to 4.6)0.86 (0.20 to 3.6)
Female sex0.65 (0.29 to 1.4)0.57 (0.21 to 1.5)0.65 (0.29 to 1.4)0.57 (0.21 to 1.5)
CRIB score‡1.3 (1.1 to 1.6), p = 0.0061.09 (0.79 to 1.5)1.3 (1.1 to 1.5), p = 0.0061.09 (0.79 to 1.5)
  • CRIB II, clinical risk index for babies; GI, gastrointestinal; IVH, intraventricular haemorrhage; NEC, necrotising enterocolitis; PVL, periventricular leukomalacia; SGA, small for gestational age.

  • *OR for each additional week of gestational age; †OR for having a birth weight less than the 10th percentile; ‡OR for each one point increment in CRIB.