Table 1 Description of included patients
Normotensive(n = 52)Permissive hypotension(n = 34)Treated hypotension(n = 18)Hypotension,transfusion only(n = 4)
Birth weight (g), mean (SD)828 (144)†742 (131)728 (149)701 (44)
Gestation (weeks), mean (SD)26.6 (1.6)26.1 (1.6)25.2 (1.62)*24.0 (0.5)
CRIB II score, mean (range)11 (7–18)11 (8–16)15 (9–16)*15 (10–20)
BP at 6 h (mm Hg), mean (range)32 (25–49)†26 (16–42)22 (14–34)*19 (17–23)
BP at 12 h (mm Hg), mean (range)34 (27–72)†27 (17–35)22 (12–32)*21 (12–25)
BP at 18 h (mm Hg), mean (range)33 (26–65)†30 (20–37)24 (13–33)*23 (13–29)
BP at 24 h (mm Hg), mean (range)35 (25–54)†31 (22–41)28 (16–36)*25 (16–31)
Antenatal steroid71%82%65%50%
Vaginal delivery35%31%32%50%
RDS76%†91%100%100%
PDA58%†83%37%67%
NEC4 (8%)3 (9%)2 (11%)2 (50%)
Surgical NEC1110
Isolated GI perforation2010
Cystic PVL1000
IVH 3–42452
Mortality10413*2
Survival without severe IVH, cystic PVL,40 (77%)26 (76%)4 (22%)*1 (25%)
surgical NEC or GI perforation, n (%)
  • BP, blood pressure; CRIB II, clinical risk index for babies; GI, gastrointestinal; IVH, intraventricular haemorrhage; NEC, necrotising enterocolitis; PDA, patent ductus arteriosus; PVL, periventricular leukomalacia; RDS, respiratory distress syndrome.

  • *Significantly different to the permissive hypotension and normotensive groups; †Significantly different to the permissive hypotension and treated hypotension groups.