Table 3 Model development: specificity and sensitivity of ⩾2 or ⩾3 clinical signs, with and without a C-reactive protein (CRP) response, for a positive blood culture (BC)
ModelSpecificity (%)Sensitivity (%)
No BC taken or negative BC (n = 3855)No BC taken (n = 3535)Negative BC (n = 320)All positiveBC (n = 99)CoNS BC (n = 73)Mixed BC* (n = 12)Known pathogen BC† (n = 14)
⩾2 clinical signs82.985.356.369.767.166.785.7
⩾2 clinical signs plus CRP response95.496.285.935.434.325.050.0
⩾3 clinical signs91.893.276.654.648.058.385.7
⩾3 clinical signs plus CRP response97.298.393.427.313.733.335.7
  • *9 mixed coagulase-negative staphylococci (CoNS), 2 CoNS and Gram-negatives, 1 Staphylococcus aureus and Gram-negative.

  • †6 S aureus, 8 Gram-negatives.