Table 1 Criteria for extubation failure in VLBW neonates1820
Blood gasespH <7.25;
Paco2 >8–9.3 kPa (60–70 mm Hg)
Inspired oxygen (Fio2)Fio2 >0.6–0.7 for saturation >92%
Frequent desaturations
SNIPPV support>26/8 cm H2O airway pressures
>19 SIMV rate
Apnoea/bradycardia/desaturationsSevere, recurrent apnoea requiring bag and mask ventilation
  • Fio2, fractional inspired oxygen; Paco2,partial pressure of carbon dioxide; SIMV, synchronous intermittent mandatory ventilation.