Table 1a Hydrocortisone and chronic lung disease

Study no.	Study	Type of study	No of patients	Treatment allocation	Mean GA	Mean BW	HC indication
1	Baden et al,22 1972	Randomised, placebo controlled	44	22 HC	32.5	1730	Prophylaxis
				22 placebo	31.8	1767
2	Watterberg et al,23 1999	Randomised, double-masked, placebo controlled pilot	40	20 HC	25.2	732	Prophylaxis
				20 placebo	25.4	770
3	Heide-Jalving et al,26 2003	Retrospective non-randomised	50	25 HC	28.3	1040	Treatment of CLD
				25 control	28.4	1090
4	Watterberg et al,27 2004	Randomised, double-masked, placebo controlled	Enrolment stopped at 360*	180 HC	25.2	731	Prophylaxis
				180 placebo	25.3	734
5	Peltoniemi et al,28 2005	Randomised, placebo controlled	Enrolment stopped at 51*	25 HC	26.7	888	Prophylaxis
				26 placebo	26.5	903
6	Bonsante et al,29 2007	Randomised, placebo controlled	Enrolment stopped at 50†	25 HC	26.2	840	Prophylaxis
			25 placebo	26.5	900