Table 2

 Sensitivity of pulse oximetry and routine follow-up with clinical examination to detect serious congenital heart defects

DefectPulse oximetry, screened newborns*Pulse oximetry, all data availableRoutine follow-up and clinical examination1
Positive/all (%)Positive/all (%)Positive/all (%)
NA, not available.
*References as in table 1; †References as in table 1 and references 9, 21.
†13/21 or 62% by exclusively postductal Spo2.
‡Includes deaths due to missed diagnosis.
Hypoplastic left heart3/3 (100)15/15 (100)23/35‡ (66‡)
Pulmonary atresia5/5 (100)14/14 (100)47/64‡ (73‡)
Ebstein’s anomaly01/1 (100)NA
Transposition of great arteries9/10 (90)35/36 (97)65/76‡ (86‡)
Common arterial trunk5/6 (83)8/9 (89)11/18 (61)
Total anomalous pulmonary venous return4/5 (80)7/8 (88)2/22 (9)
Tricuspid atresia1/1 (100)6/7 (86)NA
Double outlet right ventricle4/5 (80)6/7 (86)NA
Double inlet left ventricle04/5 (80)NA
Interrupted aortic arch08/10 (80)10/19‡ (53‡)
Aortic atresia or stenosis2/2 (100)8/10 (80)32/58‡ (55‡)
Atrioventricular septal defect3/4 (75)6/8 (75)3/19 (16)
Tetralogy of Fallot6/11 (55)15/21 (71)54/72‡ (75‡)
Coarctation of aorta5/10 (50)13/26† (50 (62)†)30/95‡ (32‡)
Pulmonary stenosis Left-to-right shunts, see text4/9 (44)6/13 (46)65/112‡ (58‡)
Total51/71 (72)152/190 (80)342/590 (58)