| Ibuprofen group (n = 60) | Indometacin group (n = 59) | |
| Age at start of treatment (hours) | 8 (4–21) | 8 (3–24) |
| Doses of medicine (number) | 1 (1–6) | 2 (1–6) |
| PDA closed after 1 dose | 32 (53.3) | 31 (52.5) |
| PDA closed after 2 doses | 10 (16.7) | 11 (18.6) |
| PDA closed after 3 doses | 3 (5) | 3 (5.1) |
| PDA closed after 4 doses | 2 (3.3) | 1 (1.7) |
| PDA closed after 5 doses | 2 (3.3) | 2 (3.4) |
| PDA closed after 6 doses | 4 (6.7) | 4 (6.8) |
| Total PDA closed | 53 (88.3) | 52 (88.1) |
| Reopening rates | 9 (15) | 8 (13.6) |
| Ligation rates | 4 (6.7) | 5 (8.5) |
*Values are median (range) or number (%). Percentages were calculated on total number of infants in each treatment group. There were no significant differences between the groups.