Table 3

 Perinatal outcome by study group. Values are n (%)

Non-SGA bothSGA population onlySGA customised onlySGA bothp Value
Intermediate groupsAll groups
CS, caesarean section; NICU, neonatal intensive care unit; OR, odds ratio; SGA, small for gestational age.
*Pearson-χ2; †exact Fisher’s test.
‡Stillborns excluded; ¶Stillborns and cases with elective caesarean section excluded; §Stillborns and cases with unavailable umbilical cord sample at birth excluded (n = 528).
Elective CS‡679 (5.9)20 (9.9)47 (8.5)141 (10.9)0.54*<0.001*
Emergent CS for distress¶304 (26)6 (3)24 (4.4)84 (6.6)0.4*<0.001*
Metabolic acidosis§54 (0.5)1 (0.5)9 (1.7)19 (1.5)0.3†<0.001*
Five-minute Apgar <7‡71 (0.6)2 (1)4 (0.7)17 (1.3)0.66†0.035*
Perinatal death65 (0.6)2 (1)10 (1.8)22 (1.7)0.74†<0.001*
    OR (95% CI)1.8 (0.4 to 7.2)3.2 (1.6 to 6.2)3 (1.9 to 4.9)
    Stillborns51 (0.4)2 (1)10 (1.8)17 (1.3)0.74†<0.001*
    Neonatal death‡14 (0.1)0 (0)0 (0)5 (0.4)0.071*
Neurological morbidity‡72 (0.6)2 (1)11 (2)17 (1.3)0.53†<0.001*
    OR (95% CI)1.6 (0.4 to 6.5)3.2 (1.7 to 6.1)2.1 (1.3 to 3.6)
    Seizures‡20 (0.2)1 (0.5)2 (0.4)5 (0.4)1†0.25*
    Intraventricular haemorrhage‡13 (0.1)1 (0.5)1 (0.2)6 (0.5)0.46†0.012*
    Periventricular leucomalacia‡3 (0)0 (0)1 (0.2)0 (0)1†0.2*
    Hypoxic-ischaemic encephalopathy‡37 (0.3)0 (0)2 (0.4)8 (0.6)1†0.29*
    Abnormal electroencephalogram‡45 (0.4)1 (0.5)6 (1.1)7 (0.5)0.68†0.1*
Non-neurological morbidity‡53 (0.5)1 (0.5)20 (3.6)17 (1.3)0.02*<0.001*
    OR (95% CI)1.1 (0.1 to 7.8)8 (4.8 to 13.6)2.9 (1.7 to 5)
    Prolonged NICU stay‡46 (0.4)1 (0.5)17 (3.1)16 (1.2)0.05†<0.001*
    Hypoglycaemia‡112 (1)0 (0)14 (2.5)42 (3.3)0.03†<0.001*
    Necrotising enterocolitis‡4 (0)0 (0)1 (0.2)2 (0.2)1†0.16*
    Acute renal or cardiac failure‡13 (0.1)0 (0)2 (0.4)3 (0.2)1†0.29*