Proportion (%) of neonates developing complications | ||
---|---|---|
Conservative treatment*(N = 30) | Medical treatment†(reference database) | |
*See Methods: Adjustment of ventilation and fluid restriction, and if PDA still present, ductal ligation. | ||
†Range based on the data from the Vermont Oxford Network and data on outcome with ibuprofen and/or indometacin, as provided by Orphan Europe (http://www.Orphan-europe.com).19–26 | ||
Necrotising enterocolitis | 0 | 4–6 |
Intraventricular haemorrhage grade 3 | 2 | 6–7 |
Chronic lung disease | 7 | 18–28 |
Death | 12 | 12 |