Results of screening for subclinical histological chorioamnionitis at one and five minutes by using perfusion index monitoring in two selected term newborn populations (phase 1 of the study)
| Variables | Histological chorioamnionitis | |
|---|---|---|
| Yes | No | |
| Where applicable, values are mean (SD). Non-normally distributed continuous variables are expressed as median (25th–75th centiles). Categorical variables are expressed as case numbers with percentages in parentheses. | ||
| Significant pairwise differences, Bonferroni corrected significance levels: *0.05<p<0.01; **0.01<p<0.0001; ***p<0.0001. | ||
| NICU, Neonatal intensive care unit; SGA, small for gestational age; SNAPE-PE, score for neonatal acute physiology-perinatal extension; NTISS, neonatal therapeutic intervention scoring system. | ||
| Number of cases | 51 | 115 |
| M:F | 23:28 | 54:61 |
| Gestational age (weeks) | 39.8 (1.3) | 39.5 (1.5) |
| Birth weight (g) | 3128 (457) | 3188 (572) |
| 1 min perfusion index | 1.74 (0.32) | 4.50 (0.83)*** |
| 5 min perfusion index | 2.18 (1.02) | 4.42 (2.10)*** |
| 1 min Apgar score | 7 (5–9) | 9 (8–10)* |
| 5 min Apgar score | 9 (8–10) | 9 (9–10) |
| 1 min core temperature (°C) | 37.02 (0.15) | 37.05 (0.05) |
| 1 min skin temperature (°C) | 34.50 (0.22) | 34.54 (0.25) |
| 5 min core temperature (°C) | 37.01 (0.25) | 37.03 (0.31) |
| 5 min skin temperature (°C) | 34.75 (0.40) | 34.81 (0.58) |
| Cord blood pH | 7.315 (0.145) | 7.346 (0.170) |
| Cord blood base excess | −5.6 (7.9) | −1.7 (4.1)** |
| Admission to NICU | 15 (29.4%) | 7 (6.1%)** |
| SGA (birth weight <3rd centile) | 5 (9.8%) | 9 (7.8%) |
| Endotracheal intubation | 5 (9.8%) | 1 (0.9%)* |
| SNAP-PE | 6 (3–10) | 0 (0–1)*** |
| NTISS | 5 (1–10) | 0 (0–1)*** |