Table 1

 Case definition of invasive fungal infection in very low birthweight infants

One or more of the following:
    • culture of fungus from a sterile site
        • blood (peripheral site, not via an indwelling catheter)
        • central intravascular catheter (“long line”) tip
        • urine (suprapubic aspirate or aseptic “in-out” urinary catheter sample)
        • cerebrospinal fluid
        • bone or joint
        • peritoneal or pleural space
    • pathognomonic findings on ophthalmological or renal ultrasound examination
    • autopsy diagnosis of invasive fungal infection