Results of the clinical observational study on six newborns from mothers who chewed betel nut during pregnancy
| Case No | Somatometry | Clinical signs | Placental morphology | Arecoline in biological matrices (μg/g) | ||||
|---|---|---|---|---|---|---|---|---|
| Birth weight (g) | Crown-heel height (cm) | Cranial perimeter (cm) | Gestation (weeks) | Meconium | Placenta | |||
| NA, Not available; ND, not detected. | ||||||||
| 1 | 3450 | 51 | 34 | 41 | None | 577 g; macro and micro normal | 0.008 | ND |
| 2 | 3090 | 49 | 34 | 38 | Neonatal withdrawal syndrome treated with 5 mg/kg phenobarbital for 3 subsequent days | 655 g; macro normal; micro acute focal chorioamnionitis | NA | 0.012 |
| 3 | 2430 | 47 | 33 | 41 | Low birth weight, low intrauterine growth, small for gestational age, hyporeflexia, hypotonia | 435 g; macro normal; micro acute focal chorioamnionitis, reduced vascular diameter | 0.006 | 0.009 |
| 4 | 3260 | 49 | 34 | 39.6 | None | 548 g; macro and micro normal | 0.022 | 0.013 |
| 5 | 2865 | 48 | 32 | 38.3 | None | 498 g; macro and micro normal | NA | 0.015 |
| 6 | 3575 | 52 | 35 | 40.4 | None | 468 g; macro and micro normal | 0.017 | 0.014 |