Day 1 | Day 2 | Day 3 | ||||
---|---|---|---|---|---|---|
Ibuprofen | Placebo | Ibuprofen | Placebo | Ibuprofen | Placebo | |
Values are mean (range).There were no significant changes between the groups. Significant changes within the groups—that is, individual changes between the starting and end point of the measurement—are indicated with an asterisk. | ||||||
ΔCBV | 0.19 (0–0.39) | 0.12 (−0.14–0.38) | 0.44 (0.23–0.66)* | 0.44 (0.17–0.70)* | 0.15 (−0.17–0.48) | 0.11 (−0.20–0.40) |
ΔTOI | 2.0 (−0.4–4.2) | −0.7 (−2.9–1.4) | 0.5 (0.2–0.7)* | 1.2 (−1.2–3.6) | −1.2 (−3.5–1.0) | −4.8 (−12.0–2.5) |
ΔHbD | 2.9 (−1.4–7.3) | 2.4 (−2.3–7.1) | 3.7 (−1.6–8.9) | 1.4 (−0.9–3.8) | 2.7 (−2.1–7.6) | 1.8 (−1.8–5.5) |
ΔHbT | 3.1 (0.1–6.1)* | 1.9 (−2.5–6.4) | 7.3 (3.6–11.1)* | 5.7 (2.4–8.9)* | 1.7 (−2.6–5.9) | 2.0 (−1.5–5.5) |
ΔSAT | −0.3 (−1.2–0.6) | −0.5 (−1.3–0.3) | −0.2 (−1.6–1.1) | −0.3 (−0.9–0.2) | −0.1 (−0.7–1.0) | 0.4 (−1.0–1.8) |
ΔHR | −0.3 (−3.5–2.9) | 0.6 (−2.2–3.5) | 1.1 (−2.5–4.8) | −1.0 (−4.7–2.6) | −2.5 (−6.5–1.5) | −1.5 (−1.7–4.7) |
ΔMABP | 0.9 (−0.5–2.1) | −0.3 (−2.5–1.7) | 0.6 (−0.8–2.0) | −0.9 (−2.4–0.5) | 2.5 (−2.5–7.6) | −0.8 (−3.1–1.1) |