Subject characteristics by study group
| LL (n = 40) | LH (n = 40) | HH (n = 39) | p Value | |
|---|---|---|---|---|
| Unless otherwise stated, values are number (%). | ||||
| *Values are mean (95% confidence interval). | ||||
| †Fisher’s exact test. | ||||
| ‡χ2 test. | ||||
| ¶Kruskal-Wallis test. | ||||
| LL, received low ascorbic acid (AA) supplementation throughout; LH, received low AA until day 10 and then high; HH, received high AA throughout; CRIB, clinical risk index for babies.23 | ||||
| Maternal ethnicity (European) | 34 (85) | 37 (93) | 34 (87) | 0.60† |
| Antenatal steroids | ||||
| Full | 21 (53) | 20 (50) | 21 (54) | 0.79† |
| Partial | 13 (33) | 17 (42) | 13 (33) | |
| Chorioamnionitis (yes) | 5 (12) | 3 (8) | 3 (8) | 0.79† |
| Caesarean section | 29 (73) | 25 (63) | 21 (54) | 0.23‡ |
| Male | 22 (55) | 25 (63) | 16 (41) | 0.15‡ |
| Hyaline membrane disease | 34 (85) | 29 (73) | 29 (74) | 0.36‡ |
| Ventilation - any | 31 (78) | 27 (68) | 25 (64) | 0.40‡ |
| Surfactant (% yes) | 29 (73) | 24 (60) | 26 (67) | 0.50‡ |
| Gestational age (weeks)* | 27.9 (27.2 to 28.6) | 28.6 (27.8 to 29.4) | 28.7 (27.8 to 29.6) | 0.29¶ |
| Birth weight (g)* | 1109 (1007 to 1210) | 1181 (1065 to 1297) | 1175 (1051 to 1300) | 0.75¶ |
| CRIB score* | 2.30 (1.43 to 3.17) | 2.15 (1.32 to 2.98) | 2.28 (1.33 to 3.24) | 0.95¶ |