Table 3

 Histological evidence of brain damage in 70 neonates

Pathological featureBA group (n = 53; asphyxiated infants)NoBA group (n = 17; non-asphyxiated infants)
Mature (n = 23)Preterm (n = 30)Mature (n = 3)Preterm (n = 14)
Values in parentheses are percentages.
Mature, ⩾37 weeks; preterm, 24–36 weeks.
Neuronal eosinophilia14 (61)9 (30)25 (36)
Neuronal karyorrhexis11 (48)8 (27)00 (0)
Grey matter infarcts1 (4)3 (10)00 (0)
White matter gliosis11 (48)14 (47)20 (0)
Grey matter gliosis7 (30)5 (17)10 (0)
Microglial upregulation9 (39)14 (47)11 (7)
Macrophages9 (39)14 (47)00 (0)
Fresh haemorrhage11 (48)19 (63)08 (57)
Haemosiderin deposits0 (0)1 (3)00 (0)
Mineral deposits2 (9)8 (27)21 (7)