Incidence of adverse outcomes in the two groups of newborns receiving prophylactic or rescue nasal continuous positive airway pressure
| Adverse outcome | Prophylaxis group (n = 115) | Rescue group (n = 115) | Newborns eligible but not randomised (n = 193) |
|---|---|---|---|
| Values are number (%). | |||
| IVH, Intraventricular haemorrhage; PVL, periventricular leucomalacia; ROP, retinopathy of prematurity; NEC, necrotising enterocolitis; CLD, chronic lung disease (O2 at 36 weeks postmenstrual age); PDA, patent ductus arteriosus (echocardiographic evidence of PDA shunting left to right regardless of haemodynamic significance). | |||
| Death ⩽7 days | 2 (1.7) | 0 | 1 (0.5) |
| Death 8–28 days | 2 (1.7) | 5 (4.3) | 3 (1.6) |
| IVH > grade 2 | 3 (2.6) | 1 (0.9) | 4 (2.1) |
| PVL | 1 (0.9) | 3 (2.6) | 10 (5.2) |
| ROP grade > grade 2 | 0 | 1 (0.9) | 0 |
| NEC | 2 (1.7) | 1 (0.9) | 1 (0.5) |
| Sepsis | 19 (16.5) | 17 (14.8) | 23 (12) |
| CLD | 2 (1.7) | 1 (0.9) | 2 (1.0) |
| Air leaks | 3 (2.6) | 3 (2.6) | 5 (2.5) |
| PDA | 19 (16.5) | 29 (25.2) | 35 (18.1) |