Characteristics of infants in the two groups (caffeine dose of 20 mg/kg/day or 5 mg/kg/day)
| 20 mg/kg (n = 113) | 5 mg/kg (n = 121) | |
|---|---|---|
| *Values are mean (SD). | ||
| †Values are number (%). | ||
| ‡Values are median (interquartile range). | ||
| Gestational age (weeks)* | 27.1 (1.4) | 27.4 (1.4) |
| Less than 28 weeks gestation† | 63 (56) | 57 (47) |
| Birth weight (g)* | 1009.2 (255.6) | 1010.5 (239.6) |
| Age at enrolment (days)‡ | 4.0 (1.9–12.0) | 3.9 (2.0–11.0) |
| Mechanical ventilation at enrolment (days)‡ | 4.7 (2.5–12.7) | 4.2 (2.29–12.41) |
| Nil antenatal steroids† | 16 (14) | 15 (12) |
| Respiratory distress syndrome† | 96 (85) | 110 (91) |
| Exogenous surfactant† | 90 (80) | 101 (84) |
| Male sex† | 55 (49) | 63 (52) |
| White† | 99 (88) | 108 (89) |
| Multiple pregnancy† | 36 (32) | 43 (36) |