Red cell indices, osmotic gradient ektacytometry variables, intracellular [Na+] and [K+] and isotopic K+ influx
Haematological indices | Osmotic gradient ektacytometry | Intracellular electrolytes (mmol/l cells) | K+ (86Rb) influx at 5 mM external [K+] (mmol/(l cells.h)) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hb (g/l) | MCV (fl) | MCHC (g/l) | Retics (%) | Stmtcyts | Omin (mosmol/kg) | DImax (arbitrary units) | O’ (mosmol/kg) | Na+ | K+ | Pump | Cotr | Leak | |
Hb, Haemoglobin; MCV, mean corpuscular volume; MCHC, mean corpuscular haemoglobin concentration; Retics, reticulocytes; Stmtcyts, stomatocytes; Omin, osmotic fragility; DI, deformability index; O’, measure of cellular hydration; Cotr, Na+/K+ cotransport. | |||||||||||||
Child | 112 | 87.4 | 372 | 5.5 | + | 125 | 0.46 | 312 | 18.4 | 88.7 | |||
Mother | 99 | 103.6 | 363 | 2.7 | + | 147 | 0.47 | 333 | 11.48 | 102.2 | 3.539 | 0.252 | 0.140 |
Father | 158 | 88.9 | 355 | 1.7 | − | 161 | 0.41 | 346 | 8.93 | 99.1 | |||
Normal | 120–180 | 85–96 | 300–350 | <2 | 143–163 | 0.41–0.53 | 335–375 | 5–11 | 85–105 | 1–2 | 0–1 | 0.05–0.10 |