Data on McCarthy scales of children’s abilities
| Etamsylate (n = 133) | Placebo (n = 131) | p Value | |
|---|---|---|---|
| Values are mean (SD). The standardised mean for the subscales is 50 in normal children and 100 for the GCI. There is a non-significant trend for the GCI and the subscales to be higher in the etamsylate group, using two sample t tests. This difference is due to the greater number of children in the placebo group with GCI ⩽ 50 (and < 70). Fisher’s exact test was used to compare the numbers in each group. | |||
| *Four in the placebo group and one in the etamsylate group were too severely affected to have a score. There were four who refused to cooperate for the McCarthy scales and all were excluded: all four were in the placebo group. | |||
| GCI, General cognitive index; IVH, intraventricular index. | |||
| GCI | 93.3 (16.2) | 89.7 (19.7) | 0.10 |
| Subscales | |||
| Verbal | 45.9 (9.6) | 43.6 (11.1) | 0.07 |
| Perceptual/performance | 48.4 (9.7) | 46.6 (11.3) | 0.17 |
| Quantitative | 45.2 (9.6) | 44.6 (11.1) | 0.6 |
| Motor | 43.3 (9.8) | 41.0 (10.8) | 0.07 |
| Memory | 44.7 (8.5) | 42.7 (10.0) | 0.07 |
| Mean GCI excluding those with a score ⩽50 | 94.3 (14.9) | 93.3 (16.2) | 0.6 |
| GCI⩽50* | 3 | 11 | 0.03 |
| Mean GCI in those with a | n = 124 | n = 112 | |
| score ⩾70 | 95.9 (13.3) | 95.6 (14.2) | 0.86 |
| GCI<70* | 6 Boys, 3 girls | 8 Boys, 11 girls | |
| Total | 9 | 19 | 0.047 |
| Mean GCI in those without | n = 116 | n = 116 | |
| cerebral palsy | 95.2 (15.3) | 93.1 (17.1) | 0.33 |
| Mean GCI in those without | n = 106 | n = 99 | |
| grade 2 or 3 IVH | 94.8 (15.4) | 92.2 (17.9) | 0.27 |