Baseline data for the 268 survivors seen
Baseline data | Etamsylate | Placebo |
---|---|---|
*Standard deviation in parentheses. | ||
†In first four days. | ||
PVH, Periventricular haemorrhage. | ||
Singleton/multiple birth | 97 (73%)/36 (27%) | 97 (72%)/38 (28%) |
Male/female | 50 (38%)/83 (62%) | 65 (48%)/70 (52%) |
Birth weight (g)* | 1154 (210) | 1166 (217) |
Gestational age (weeks)* | 29.5 (2.3) | 29.6 (2.4) |
Apgar score (5 min) <7 | 18 (13.5%) | 24 (17.8%) |
Caesarean section | 73 (55%) | 83 (61%0 |
Respiratory distress† | 80 (60%) | 88 (65%) |
Artificial ventilation† | 89 (67%) | 96 (71%) |
Acidosis pH <7.15† | 40 (30%) | 34 (25%) |
Hypercapnoea (Paco2>60 mm Hg or >8.2 kPa) | 40 (30%) | 36 (27%) |
Pneumothorax† | 4 (3%) | 5 (4%) |
Grade 3 PVH | 11 (8%) | 13 (10%) |
Grade 2 PVH | 16 (12%) | 20 (15%) |
Grade 1 PVH | 15 (11%) | 10 (7%) |
No PVH | 91 (68%) | 92 (68%) |
Maternal smoking | 59 (44%) | 55 (41%) |
Maternal age at birth (years)* | 27.8 (5.8) | 26.9 (6.0) |
Centre | ||
Bath | 11 (8%) | 12 (9%) |
Blackburn | 21 (16%) | 25 (18%) |
Bristol (BMH & Southmead) | 40 (30%) | 40 (30%) |
Cardiff | 15 (11%) | 11 (8%) |
Liverpool | 46 (35%) | 47 (35%) |
Social class | ||
1 | 3 (2%) | 7 (5%) |
2 | 22 (17%) | 15 (11%) |
3 | 65 (49%) | 61 (45%) |
4 | 14 (10%) | 6 (4%) |
5 | 3 (2%) | 1 (1%) |
Unemployed | 26 (20%) | 45 (34%) |
Total | 133 | 135 |