Comparison of infants who did and did not frequently wheeze
| Frequent wheeze (n=37) | Non-frequent wheeze (n=148) | p Value | |
|---|---|---|---|
| Data are expressed as mean, median (range). | |||
| PMA, Postmenstrual age. | |||
| Gestational age (weeks) | 26.6, 26.4 (23.6–28.9) | 26.6, 26.8 (23.0–28.9) | 0.95 |
| Birth weight (g) | 899, 870 (590–1459) | 882, 873 (500–1430) | 0.81 |
| Maternal smoking (%) | |||
| In pregnancy | 22 | 20 | 0.83 |
| After birth | 20 | 22 | 0.84 |
| Family history of atopy (%) | 49 | 57 | 0.34 |
| Duration (days) of | |||
| Ventilation | 25.6, 21 (1–75) | 17.3, 11.5 (0–112) | 0.013 |
| Supplementary oxygen | 84.4, 67 (20–239) | 69.3, 73 (1–179) | 0.42 |
| Oxygen dependency (%) | |||
| At 28 days | 97 | 87 | 0.08 |
| At 36 weeks | 76 | 70 | 0.47 |
| At discharge | 43 | 29 | 0.09 |
| Chest radiograph score at 28 days | |||
| Total | 4.2, 4 (1–8) | 3.4, 3 (0–7) | 0.020 |
| Fibrosis | 2.9, 3.0 (1–4) | 2.4, 2 (0–4) | 0.017 |
| Cystic elements | 0.2, 0 (0–2) | 0.1, 0 (0–2) | 0.17 |
| Hyperinflation | 1.1, 1 (0–2) | 0.9, 1 (0–2) | 0.17 |
| Chest radiograph score at 36 weeks PMA | |||
| Total | 4.5, 5 (0–8) | 3.5, 3 (0–7) | 0.005 |
| Fibrosis | 3.1, 4 (0–4) | 2.4, 2 (0–4) | 0.001 |
| Cystic elements | 0.2, 0 (0–2) | 0.1, 0 (0–1) | 0.0007 |
| Hyperinflation | 1.1, 1 (0–2) | 1.1, 1 (0–2) | 0.67 |