Coagulation status in each gestational age group within two hours of birth
| Gestational age (weeks) | n | Factor II (%) | Factor V (%) | Factor VII (%) | Factor X (%) | Platelets (× 109/l) | APTT† (s) | PT-INR† |
|---|---|---|---|---|---|---|---|---|
| *p<0.05 compared with gestational age 34–36 weeks; †Data available for 101 infants; ‡at the age of 1 day.1 | ||||||||
| APTT, Activated partial thromboplastin time; PT, prothrombin time; INR, international normalised ratio. | ||||||||
| 24–27 | 21 | |||||||
| Mean (SD) | 31 (9)* | 57 (20)* | 43 (16)* | 35 (10) | 181 (71)* | 49 (8) | 1.4 (0.3) | |
| Median | 30 | 61 | 46 | 34 | 166 | 48 | 1.4 | |
| Range | 20–49 | 10–102 | 14–81 | 23–56 | 77–338 | 28–36 | 1.1–2.0 | |
| 28–30 | 25 | |||||||
| Mean (SD) | 30 (8)* | 67 (25) | 50 (22)* | 36 (9) | 214 (64)* | 46 (10) | 1.4 (0.2) | |
| Median | 29 | 65 | 51 | 34 | 225 | 45 | 1.3 | |
| Range | 17–47 | 29–113 | 15–103 | 20–55 | 59–322 | 30–72 | 1.0–2.2 | |
| 31–33 | 34 | |||||||
| Mean (SD) | 39 (13) | 78 (28) | 64 (28) | 44 (15) | 237 (34) | 44 (22) | 1.4 (0.7) | |
| Median | 37 | 73 | 62 | 42 | 238 | 41 | 1.3 | |
| Range | 13–64 | 5–136 | 11–134 | 9–72 | 59–416 | 28–145 | 0.9–4.5 | |
| 34–36 | 45 | |||||||
| Mean (SD) | 38 (10) | 76 (26) | 63 (23) | 40 (10) | 255 (45) | 46 (28) | 1.3 (0.3) | |
| Median | 37 | 73 | 63 | 39 | 261 | 41 | 1.3 | |
| Range | 13–64 | 17–143 | 12–114 | 22–63 | 52–434 | 27–200 | 1.1–2.7 | |
| Term infant‡ | 48 (11) | 72 (18) | 66 (19) | 40 (14) | 43 (6) | |||