Table 2

Comparison of early perinatal characteristics in infants with necrotising enterocolitis cared for in centres with on site surgical facilities (group 1) and in centres without (group 2)

Variable Group 1 Group 2 p Value Odds ratio (95% CI)
No of infants5272
Gestation (weeks)26.2 (1.3)26.2 (1.4)1.00
Birth weight (g)887 (241)889 (225)0.96
Male sex26 (50%)40 (55%)0.800.59 (0.39 to 1.64)
Pre-eclampsia6 (12%)6 (8%)0.771.21 (0.38 to 3.84)
Antepartum haemorrhage19 (37%)18 (25%)0.231.73 (0.79 to 3.76)
Growth restriction6 (12%)6 (8%)0.561.44 (0.44 to 4.73)
Antenatal corticosteroids37 (71%)62 (86%)0.070.40 (0.23 to 1.08)
Apgar at 5 min7.0 (1.7)7.2 (1.7)0.52
CRIB score5.9 (3.7)5.8 (4.0)0.89
HMD39 (75%)59 (82%)0.380.66 (0.28 to 1.58)
Surfactant treatment31 (60%)45 (63%)0.850.89 (0.43 to 1.84)
Pneumothorax11 (21%)3 (4%)0.0042-150 6.17 (1.63 to 23.43)
Indomethacin for PDA20 (39%)19 (26%)0.171.74 (0.81 to 3.75)
PDA surgery7 (14%)4 (6%)0.202.64 (0.73 to 9.56)
IVH (grade 3–4)3 (6%)8 (11%)0.360.49 (0.12 to 1.94)
  • Values are mean (SD) or number (%).

  • 2-150 p<0.05.

  • HMD, hyaline membrane disease; PDA, patent ductus arteriosus; IVH, intraventricular haemorrhage.