Variable | Group 1 | Group 2 | p Value | Odds ratio (95% CI) |
No of infants | 605 | 1195 | ||
Gestation (weeks) | 26.3 (1.4) | 26.4 (1.4) | 0.15 | |
Birth weight (g) | 919 (231) | 929 (226) | 0.38 | |
Male sex | 318 (53%) | 613 (51%) | 0.62 | 1.05 (0.86 to 1.28) |
Pre-eclampsia | 82 (14%) | 175 (15%) | 0.57 | 0.91 (0.69 to 1.21) |
Antepartum haemorrhage | 180 (30%) | 357 (30%) | 1.00 | 0.99 (0.80 to 1.23) |
Growth restriction | 34 (6%) | 67 (6%) | 1.00 | 1.00 (0.66 to 1.53) |
Antenatal corticosteroid | 449 (74%) | 1016 (85%) | <0.00011-150 | 0.51 (0.40 to 0.65) |
Apgar at 5 min | 7.0 (1.8) | 7.1 (1.8) | 0.27 | |
HMD | 483 (80%) | 862 (72%) | 0.00041-150 | 1.53 (1.21 to 1.94) |
Surfactant treatment | 362 (60%) | 754 (63%) | 0.18 | 0.87 (0.71 to 1.07) |
Pneumothorax | 85 (14%) | 120 (10%) | 0.021-150 | 1.46 (1.09 to 1.97) |
Proven NEC | 52 (9%) | 72 (6%) | 0.0481-150 | 1.47 (1.01 to 2.13) |
IVH (grade 3–4) | 61 (10%) | 128 (11%) | 0.75 | 0.94 (0.68 to 1.29) |
Death | 162 (27%) | 324 (27%) | 0.91 | 0.98 (0.79 to 1.23) |
Steroid for CLD | 205 (34%) | 434 (36%) | 0.32 | 0.90 (0.73 to 1.10) |
ROP (grade 3–4) | 85 (14%) | 19 (9%) | 0.0021-150 | 1.63 (1.20 to 2.20) |
Ventilation (days) | 15.0 (17.5) | 17.7 (20.0) | 0.0031-150 | |
Oxygen (days) | 47.1 (49.0) | 40.4 (45.6) | 0.0051-150 | |
TPN (days) | 14.1 (16.9) | 13.9 (14.0) | 0.80 | |
Hospital stay (days) | 59.5 (49.4) | 61.5 (44.6) | 0.40 |
Values are mean (SD) or number (%).
↵1-150 p<0.05.
HMD, Hyaline membrane disease; NEC, necrotising enterocolitis; IVH, intraventricular haemorrhage; CLD, chronic lung disease; ROP, retinopathy of prematurity; TPN, total parenteral nutrition.