Table 2

Suggested indications for N-acetylcysteine treatment in neonatal paracetamol poisoning

Transplacentally acquired poisoning Oral poisoning
Potentially toxic maternal overdose (adult criteria)Ingested dose >150 mg/kg
Maternal hepatotoxicityFour hour paracetamol level above 150 treatment line on adult nomogram
Significant increase in Tβ compared with estimated normal Tβ for ageSignificant increase in Tβ compared with estimated normal Tβ for age