Generalised logistic regression analyses for respiratory distress syndrome and poor outcomes (chronic lung disease, adverse neurological findings, and death)
| Risk factor | RDS (n=5505) | CLD (n=4360) | Adverse neuro (n=3955) | Death (n=5505) |
|---|---|---|---|---|
| Values are odds ratios (95% confidence interval). | ||||
| RDS, Respiratory distress syndrome; CLD, chronic lung disease; SGA, small for gestational age; neuro, neurological findings. | ||||
| Multiplicity | ||||
| Singletons | 1.0 | 1.0 | 1.0 | 1.0 |
| Twins | 1.58 (1.32 to 1.89) | 0.96 (0.76 to 1.22) | 1.09 (0.88 to 1.33) | 1.12 (0.93 to 1.37) |
| Triplets | 2.51 (1.87 to 3.37) | 0.69 (0.46 to 1.02) | 1.29 (0.91 to 1.85) | 1.54 (1.13 to 2.11) |
| Maternal hypertension | 1.46 (1.22 to 1.75) | 1.06 (0.81 to 1.40) | 0.70 (0.54 to 0.91) | 0.69 (0.53 to 0.91) |
| Ethnic origin (non-Jews) | 1.05 (0.91 to 1.21) | 0.97 (0.83 to 1.14) | 0.96 (0.82 to 1.12) | 1.03 (0.9 to 1.19) |
| Week at start of prenatal care | ||||
| 0 to 12 | 1.0 | 1.0 | 1.0 | 1.0 |
| 13 to 20 | 0.86 (0.69 to 1.07) | 0.90 (0.66 to 1.22) | 1.18 (0.9 to 1.56) | 1.11 (0.85 to 1.45) |
| >20 or none | 1.07 (0.82 to 1.40) | 1.20 (0.79 to 1.82) | 1.30 (0.94 to 1.78) | 1.56 (1.16 to 2.1) |
| Unknown | 0.95 (0.68 to 1.33) | 1.02 (0.61 to 1.69) | 1.09 (0.68 to 1.73) | 2.41 (1.66 to 3.5) |
| Antenatal steroid therapy | ||||
| Full | 1.0 | 1.0 | 1.0 | 1.0 |
| Partial | 1.53 (1.27 to 1.86) | 0.9 (0.69 to 1.18) | 1.47 (1.15 to 1.88) | 1.04 (0.82 to 1.31) |
| None | 2.01 (1.72 to 2.35) | 1.10 (0.88 to 1.38) | 2.52 (2.06 to 3.07) | 2.0 (1.67 to 2.4) |
| Gestational age (decrease of 1 week) | 1.58 (1.53 to 1.64) | 2.19 (2.05 to 2.34) | 1.33 (1.27 to 1.4) | 1.66 (1.58 to 1.73) |
| Male sex | 1.25 (1.09 to 1.42) | 1.68 (1.40 to 2.02) | 1.3 (1.1 to 1.54) | 1.18 (1.0 to 1.38) |
| SGA | 0.81 (0.69 to 0.96) | 3.03 (2.20 to 4.1) | 1.3 (1.01 to 1.67) | 4.31 (3.41 to 5.44) |
| Vaginal delivery | 0.7 (0.6 to 0.82) | 1.0 (0.80 to 1.25) | 1.27 (1.05 to 1.53) | 1.42 (1.19 to 1.7) |
| Resuscitation at birth | 3.29 (2.72 to 3.97) | 1.98 (1.31 to 2.98) | 2.04 (1.39 to 3.0) | 1.55 (1.12 to 2.16) |
| RDS | – | 5.03 (3.91 to 6.47) | 2.0 (1.6 to 2.51) | 1.82 (1.45 to 2.27) |