Maximal changes in heart rate and mean arterial blood pressure in 16 infants within five minutes of receiving placebo and three different doses of ketamine as premedication in random order
| Dose (mg/kg) | Heart rate change (beats/min) | Blood pressure change (mm Hg) |
| Placebo | 3 (−4 to 9) | 0 (−2 to 3) |
| 0.5 | 0 (−7 to 7) | 4 (1 to 6) |
| 1 | 1 (−11 to 13) | 1 (−3 to 5) |
| 2 | −7 (−12 to 1)2-150 | −1 (−4 to 2) |
Values are mean of the difference (95% confidence interval).
↵2-150 p<0.05 compared with placebo.