Prevalence of CNS/ANS signs
| CNS/ANS signs | NON n=7442 % | EXP n=1185 % | EXP/NON Unadjusted OR (95% CI)* | CO n=717 % | OP n=100 % | OP+CO n=92 % |
|---|---|---|---|---|---|---|
| Groups: non-exposed (NON), exposed (EXP), and confirmed cocaine (CO) only, opiates (OP) only, and opiates + cocaine (OP+CO) exposure. The unadjusted OR for EXP/NON with 95% CI are also shown. | ||||||
| *All p values ≤0.05. | ||||||
| Jittery, tremors | 5.9 | 16.6 | 3.15 (2.5 to 4.0) | 14.6 | 22.2 | 43.5 |
| Irritability | 5.8 | 14.9 | 2.86 (2.3 to 3.6) | 12.2 | 24.4 | 40.2 |
| High pitched cry | 1.5 | 4.0 | 2.79 (1.8 to 4.4) | 2.8 | 11.4 | 14.9 |
| Hypertonia | 0.8 | 3.2 | 4.27 (2.6 to 7.1) | 2.0 | 7.8 | 9.8 |
| Hyperalertness | 0.1 | 1.3 | 13.10 (5.3 to 32.7) | 0.8 | 1.0 | 5.4 |
| Hyperactive | 0.3 | 1.1 | 4.43 (1.9 to 10.5) | 0.4 | 4.4 | 5.4 |
| Difficult to console | 1.0 | 2.9 | 3.10 (1.8 to 5.2) | 2.0 | 5.6 | 9.8 |
| Difficult to arouse | 0.4 | 1.0 | 2.72 (1.2 to 6.4) | 1.3 | 0 | 1.1 |
| Excessive suck | 0.7 | 3.4 | 5.30 (3.2 to 8.8) | 2.3 | 5.3 | 15.6 |
| Poor suck | 2.7 | 4.4 | 1.65 (1.1 to 2.5) | 3.9 | 4.2 | 4.4 |
| Nasal stuffiness | 1.7 | 3.0 | 1.77 (1.1 to 2.9) | 2.7 | 1.0 | 9.8 |
| Sneezing | 3.1 | 4.2 | 1.36 (1.9 to 2.1) | 3.4 | 7.3 | 7.6 |
| Any ≥1 signs | 16.6 | 30.7 | 2.23 (1.9 to 2.7) | 28.2 | 44.8 | 62.0 |