Table 1

Serum drug concentrations of patient 2

Day 5 Day 15
Paroxetine (μg/l)1-150
 MotherNot done792
 Infant48<10
Desipramine (μg/l)1-151
 Mother1064522
 Infant70<10

  • ↵1-150 Although there is no close correlation between serum concentrations and effects of paroxetine, 20 mg/day of the drug typically results in serum concentrations of about 12–90 μg/l in adults.

  • ↵1-151 The usual therapeutic concentration of desipramine is 125–300 μg/l.