Table 4

Plasma concentrations of PICP, ICTP, PIIINP and IGFBP-1 for the whole study group and in the AGA, LGA, and SGA subgroups (median and quartiles)

Variable All infants (n=67) AGA (n=39) LGA (n=11) SGA (n=17)
PICP (μg/l) (median)  quartiles1396.01398.01411.01231.0
995.3; 1651.5981.0; 1648.51178.5; 1818.8991.8; 1659.3
ICTP (μg/l) (median)  quartiles84.693.965.94-150 71.24-150
66.7; 103.477.0; 109.360.6; 90.458.6; 91.0
PIIINP (μg/l) (median)  quartiles75.476.0106.14-150 55.5
56.1; 104.759.7; 94.672.5; 123.344.3; 102.2
PICP/ICTP (median)  quartiles15.912.723.74-150 15.9
12.1; 21.211.6; 17.816.5; 25.213.7; 21.5
n=36n=15n=10n=12
IGFBP-1 (μg/l) (median)44.040.019.04-150 110.04-150
  quartiles23.0; 44.029.3; 71.59.9; 32.073.0; 172.0
  • 4-150 p < 0.05 v AGA.

  • PIIINP, collagen type III N-terminal propeptide; PICP, collagen type I C-terminal propeptide; ICTP, C-terminal cross linked telopeptide; IGFBP-1, insulin-like growth factor binding protein-1; AGA, appropriate for gestational age; LGA, large for gestational age; SGA, small for gestational age.