Univariate analysis of conditions associated with cerebral white matter lesions
| Variables | White matter lesions (n=38) | No white matter lesions (n=185) | p Value |
|---|---|---|---|
| Values in parentheses are percentages. | |||
| PDA, Patent ductus arteriosus; PROM, prolonged rupture of membranes; CRIB, clinical risk index in babies. | |||
| Male | 19 (50) | 96 (52) | |
| Female | 19 (50) | 89 (48) | 0.86 |
| Gestational age (weeks) | |||
| ≤25 | 18 (47) | 36 (19) | |
| 26–28 | 13 (34) | 63 (34) | |
| ≥29 | 7 (18) | 86 (46) | 0.0004 |
| Birth weight (g) | |||
| ≤750 | 18 (47) | 45 (24) | |
| 750–1250 | 17 (45) | 96 (52) | |
| ≥1251 | 3 (8) | 44 (24) | 0.007 |
| Antenatal steroids | |||
| No/incomplete steroids | 18 (47) | 53 (29) | |
| Complete course(s) | 20 (53) | 132 (71) | 0.03 |
| Pre-eclampsia | 8 (21) | 48 (26) | 0.68 |
| Mode of delivery | |||
| Vaginal | 24 (63) | 90 (49) | |
| Caesarean section | 14 (37) | 95 (51) | 0.11 |
| Duration of PROM | |||
| ≤24 hours | 15/22 (68) | 58/113 (51) | |
| >24 hours | 7/22 (32) | 55/113 (49) | 0.17 |
| PDA requiring indomethacin | 14 (37) | 34 (18) | 0.017 |
| Sepsis | 20 (53) | 73 (39) | 0.15 |
| Survivors | 22 (58) | 152 (82) | 0.002 |
| CRIB score | |||
| 0–5 | 19 (50) | 136 (74) | |
| 6–10 | 13 (34) | 31 (17) | |
| 11–15 | 5 (13) | 17 (9) | |
| 16 or more | 1 (3) | 1 (1) | 0.015 |