Comparison of infants <30 weeks gestational age who did and did not fail extubation
| Failure (n=6) | Success (n=7) | p Value | |
|---|---|---|---|
| Data are median (range). | |||
| CRS, compliance of the respiratory system; IP, inspiratory pressure; MIP, maximum inspiratory pressure; PIP, peak inspiratory pressure; Fio2, inspired oxygen concentration. | |||
| Gestational age (weeks) | 27 (25–28) | 29 (27–29) | <0.01 |
| Birth weight (g) | 899 (685–1606) | 1170 (938–1440) | NS |
| Postnatal age (days) | 9.5 (5–14) | 2 (2–7) | <0.01 |
| Max PIP (cm H2O) | 22 (18–23) | 19 (17–20) | <0.03 |
| Max Fio2 | 0.56 (0.31–0.65) | 0.40 (0.28–0.84) | NS |
| PIP before extubation | 12.5 (11–15) | 12 (11–13) | NS |
| Fio2 before extubation | 0.30 (0.22–0.38) | 0.22 (0.21–0.36) | NS |
| CRS (ml/cm H2O/kg) | 0.80 (0.47–1.16) | 0.77 (0.50–1.02) | NS |
| Inspiratory pressures | |||
| Mean IP (cm H2O) | 11.7 (7.3–19.7) | 16.4 (12–24.6) | <0.04 |
| Max IP (cm H2O) | 18.3 (12.7–25.1) | 21.3 (13.3–37.0) | NS |
| Max MIP (cm H2O) | 23.2 (12.7–30.0) | 32.7 (21.3–62.6) | <0.05 |
| Mean MIP (cm H2O) | 15.6 (9.9–21.2) | 25.2 (18.0–45.7) | <0.01 |