Table 2

Comparison of infants <30 weeks gestational age who did and did not fail extubation

Failure (n=6)Success (n=7)p Value
Data are median (range).
CRS, compliance of the respiratory system; IP, inspiratory pressure; MIP, maximum inspiratory pressure; PIP, peak inspiratory pressure; Fio2, inspired oxygen concentration.
Gestational age (weeks)27 (25–28)29 (27–29)<0.01
Birth weight (g)899 (685–1606)1170 (938–1440)NS
Postnatal age (days)9.5 (5–14)2 (2–7)<0.01
Max PIP (cm H2O)22 (18–23)19 (17–20)<0.03
Max Fio20.56 (0.31–0.65)0.40 (0.28–0.84)NS
PIP before extubation12.5 (11–15)12 (11–13)NS
Fio2 before extubation0.30 (0.22–0.38)0.22 (0.21–0.36)NS
CRS (ml/cm H2O/kg)0.80 (0.47–1.16)0.77 (0.50–1.02)NS
Inspiratory pressures
    Mean IP (cm H2O)11.7 (7.3–19.7)16.4 (12–24.6)<0.04
    Max IP (cm H2O)18.3 (12.7–25.1)21.3 (13.3–37.0)NS
    Max MIP (cm H2O)23.2 (12.7–30.0)32.7 (21.3–62.6)<0.05
    Mean MIP (cm H2O)15.6 (9.9–21.2)25.2 (18.0–45.7)<0.01