Changes of osmolality (mosmol/kg H2O) of human milk (HM) after supplementation with different human milk fortifiers (HMF) at various concentrations; (Values are expressed as mean (SD))
N = | HM | HMF | HM+HMF (theoretical) | After 10 minutes | After 24 hours at 4°C | |
---|---|---|---|---|---|---|
HMF1 | 6 | 297 (8) | 34 (1) | 330 (8) | 331 (12) | 338 (12)2-150 † |
HMF2(2.5%) | 10 | 291 (15) | 45 (2) | 336 (14) | 350 (13)2-150 | 371 (16)2-150 † |
HMF2(5%) | 7 | 283 (9) | 88 (2) | 371 (8) | 395 (12)2-150 | 436 (21)2-150 † |
HMF3(2.5%) | 4 | 279 (10) | 38 (1) | 317 (1) | 335 (14)2-150 | 363 (11)2-150 † |
HMF3(5%) | 6 | 281 (9) | 72 (4) | 354 (7) | 385 (12)2-150 | 449 (16)2-150 † |
HMF4(4%) | 7 | 284 (7) | 94 (2) | 377 (9) | 401 (10)2-150 | 408 (10)2-150 † |
HMF5(4%) | 7 | 284 (6) | 77 (2) | 361 (8) | 388 (10)2-150 | 406 (13)2-150 † |
↵2-150 p<0.01 vs theoretical osmolality;†p<0.01 vs values of osmolality after 10 minutes from fortification.