Na+,K+-ATPase activity in purified erythrocyte membranes and the intracellular sodium ([Na+]ic) and potassium ([K+]ic) concentrations in the three groups
|
Group 1 (preterm neonates, 28–32 weeks) |
Group 2 (preterm neonates, 33–36 weeks) |
Group 3 (term neonates, 37–42 weeks) | |
| Number of patients enrolled | 56 | 58 | 122 |
| Na+,K+-ATPase | 624 (337)2-150 | 481 (195)2-151 | 404 (167) |
| (nmol ATP/h/mg protein) | (n=37) | (n=54) | (n=113) |
| [Na+]ic (mmol/l) | 7.09 (1.03) | 7.22 (1.53) | 8.04 (1.01)2-152 |
| (n=24) | (n=56) | (n=17) | |
| [K+]ic (mmol/l) | 94.0 (13.3) | 92.3 (11.0) | 89.8 (15.5) |
| (n=16) | (n=29) | (n=18) |
Values are means (SD).
↵2-150 p < 0.05 v groups 2 and 3 (one factor analysis of variance; Fisher protected least squares difference test);
↵2-151 p < 0.05 v group 3 (one factor analysis of variance; Fisher protected least squares difference test);
↵2-152 p < 0.05 v groups 1 and 2 (one factor analysis of variance; Fisher protected least squares difference test); n = number of patients contributing to the given measurement. See the text for details.