Glucose-6-phosphatase activity in human liver microsomes
| Source of hepatic microsomal samples | Vmax(nmol/min/mg) | Km (mM) |
| All preterm infant study group (n=36) | 109(13)2-150 | 0.97 (0.11) |
| Control term infants (n=20) | 340(40) | 0.80 (0.10) |
| Study group without therapeutic insulin (n=22) | 76(12) | 0.97 (0.13) |
| Study group with therapeutic insulin ( n=14) | 162 (23)2-151 | 0.97 (0.21) |
| Study group without RDS (n=7) | 50 (16) | 0.90 (0.27) |
| Study group with RDS (n=29) | 124 (15)2-152 | 0.99 (0.12) |
| Study group without dopamine (n=29) | 122 (15) | 1.09 (0.13) |
| Study group with dopamine (n=7) | 57 (16) | 0.60 (0.12) |
Results are mean (SE).
↵2-150 p < 0.0001 compared with control term infants;
↵2-151 p < 0.0008 compared with study group without insulin treatment;
↵2-152 p < 0.05 compared with study group without RDS (respiratory distress syndrome). p values were calculated with Student's ttest using the Instat program for Macintosh computers.