Bronchopulmonary dysplasia: high frequency ventilation (HFV) versus conventional ventilation (CV)
| Reference | HFV event observed/ total No of patients | CV event observed /total No of patients | Relative risk (95% CI) |
|---|---|---|---|
| Froese, 1987 | 0/6 | 2/9 | 0.29 (0.02, 5.08) |
| HIFI, 1989 | 130/327 | 141/346 | 0.98 (0.81, 1.17) |
| Carlo, 1990 | 7/18 | 7/16 | 0.89 (0.04, 1.98) |
| Clark, 1992 | 9/30 | 17/26 | 0.46 (0.25, 0.85) |
| Ogawa, 1993 | 17/46 | 15/46 | 1.13 (0.65, 1.99) |
| Gerstmann, 1996 | 15/64 | 27/61 | 0.53 (0.31, 0.89) |
| Wiswell, 1996 | 21/37 | 23/36 | 0.89 (0.61, 1.29) |
| Keszler, 1997 | 37/55 | 37/52 | 0.95 (0.73, 1.22) |
| Rettwitz-Volk, 1998 | 18/21 | 14/20 | 1.22 (0.88, 1.71) |
| Total for all studies | 254/604 | 283/612 | 0.90 (0.80, 1.02) |
| Total for HLVS subgroup | 96/216 | 110/205 | 0.83 (0.69, 0.99) |
| Total for surfactant subgroup | 108/223 | 116/215 | 0.89 (0.75, 1.06) |
| Total for HFOV subgroup | 189/494 | 216/508 | 0.90 (0.77, 1.04) |
| Total for HFJV subgroup | 65/110 | 67/104 | 0.92 (0.75, 1.13) |
HFV=high frequency ventilation; HFOV=high frequency oscillatory ventilation; HFJV=high frequency jet ventilation; CV=conventional ventilation; RDS=respiratory distress syndrome; BPD=bronchopulmonary dysplasia; CLD=chronic lung disease; HLVS=high lung volume strategy; RR=relative risk; CI=confidence interval.