Table 4

Effect of theophylline administration on respiratory function in 16 infants

Before After 12 h Mean difference before-after12 h After 48 h Mean difference before-after48 h
Crs (ml/kPa/kgPa)16.618.34-150 1.73 (0.28)18.84-150 2.23 (0.62)
Rrs(kPa/l/s)7.16.84-151 −0.31 (0.09)6.74-151 −0.43 (0.13)
TC (s)0.230.264-151 0.02 (0.01)0.244-151 0.02 (0.01)
TV (m//kg)7.58.14-151 0.58 (0.28)8.64-151 1.11 (0.36)
  • Data are expressed as mean (SEM).

  • 4-150 p < 0.05,

  • 4-151 p > 0.05 compared with value before theophylline treatment.

  • Crs, Respiratory system compliance; Rrs, respiratory system resistance; TC, expiratory time constant; TV, tidal volume.