Outcome of NEC infants before and after introduction of routine testing of all suspected NEC infants for T and Tk-antigen activation in September 1991
| Outcome | Routine testing | Unadjusted odds ratio (95% CI) | p Value | Adjusted odds ratio (95% CI) | p Value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Before | After | ||||||||||
| No of NEC infants | 110 | 91 | |||||||||
| Birthweight (g) (mean (SD)) | 1304 (644) | 1150 (459) | 0.06 | ||||||||
| Gestation (weeks) (mean (SD)) | 29.5 (3.8) | 28.3 (2.7) | 0.01 | ||||||||
| Antepartum haemorrhage (n) | 14 (13%) | 27 (30%) | 0.003 | ||||||||
| Hypertensive disease of pregnancy (n) | 24 (22%) | 10 (11%) | 0.04 | ||||||||
| Growth restriction (< 10th percentile) | 16 (15%) | 5 (5%) | 0.04 | ||||||||
| Antenatal steroids (n) | 19 (17%) | 67 (74%) | <0.0001 | ||||||||
| Apgar score at 5 minutes (SD) | 7.7 (1.5) | 7.4 (1.7) | 0.15 | ||||||||
| Surgery for NEC | 35 (32%) | 51 (56%) | 2.7 (1.5, 4.9) | 0.0006 | 1.8 (0.9, 3.7) | 0.1 | |||||
| Died | 12 (11%) | 22 (24%) | 2.6 (1.2, 5.6) | 0.01 | 2.0 (0.8, 5.2) | 0.1 | |||||